-Medicine

If you understand how drugs work (pharmacodynamics), how they are handled by the body (pharmacokinetics), how they interact with each other, and how drug treatments are assessed, then you will become a better prescriber. A Textbook of Clinical Pharmacology and Therapeutics gives you that understanding.
Fully revised throughout and extensively illustrated, the fifth edition of this well-established textbook has been streamlined to focus on what medical students and junior doctors really need to know in order to understand the implications of prescribing one drug over, or in combination with, another. The text provides current information on all areas of drug prescribing with updated discussion and guidance on such topics as adverse drug reactions, personalized medicine, gene and cell-based therapy, advances in cancer therapy, and mechanisms of drug action and treatment guidelines in HIV and mycobacterial infections therapy. A new chapter on alternative medicines and nutraceuticals has been introduced and Further Reading lists have been updated to include key medical websites.
All medical students and junior doctors who read this book will learn not only how to use drugs safely and effectively, but, importantly, the rationale behind effective prescribing decisions.

Antimicrobial Agents: Antibacterials and Antifungals is a significant revision of an original French reference published by Ellipses in 1999. * Offers hundreds of antibiotics and antimicrobial compounds: in development, experimental, and in use * Provides a thorough update of the original French edition published in 1999, plus critical new material * Presents comprehensive coverage of chemistry and synthesis, classification, structure-activity relationships, mechanisms of action and resistance, breakpoints, in vitro/in vivo activities, epidemiology, pharmacokinetics, metabolism, and adverse events * Features over 1,200 illustrations, over 1,500 tables, and more than 3,000 references * Presents new, extensive chapters covering helicobacter pylori and methicillin-resistant Staphylococcus aureus (MSRA)

The most up-to-date, comprehensive, and authoritative pharmacology text in health medicine

Enhanced by more than three hundred illustrations -- many in full color

Organized to reflect the syllabi in many pharmacology courses and in integrated curricula, Basic & Clinical Pharmacology, 12e covers the important concepts students need to know about the science of pharmacology and its application to clinical practice. Selection of the subject matter and order of its presentation are based on the authors’ many years experience in teaching this material to thousands of medical, pharmacy, dental, podiatry, nursing, and other health science students.

To be as clinically relevant as possible, the book includes sections that specifically address the clinical choice and use of drugs in patients and the monitoring of their effects, and case studies that introduce clinical problems in many chapters. Presented in full color and enhanced by more than three hundred illustrations, Basic & Clinical Pharmacology features numerous summary tables and diagrams that encapsulate important information.

Coverage that spans every aspect of medical pharmacology:

• Basic principles
• Autonomic drugs
• Cardiovascular-renal drugs
• Drugs with important actions on smooth muscles
• Central nervous system drugs
• Drugs used to treat anemias, clotting disorders, hyperlipidemia, and inflammation and gout
• Endocrine drugs
• Chemotherapeutic and immunologic drugs
• Toxicology
• Special subjects (perinatal, geriatric, and dermatologic pharmacology)
• Botanical and "food supplements," and over-the-counter medications
• Prescribing

Also in this edition:

• Drug Summary Tables conclude most chapters, providing a concise summary of the most important drugs
• General concepts relating to newly discovered receptors, receptor mechanisms, and drug transporters
• Descriptions of important new drugs, including monoclonal antibodies

The second edition of this popular textbook provides an introduction to the principles and methods of epidemiology. Since publication of the first edition in 1993, Basic epidemiology has become a standard reference for education, training and research in the field of public health and has been translated into more than 25 languages. It is used widely, for training public health and environment professionals, undergraduate medical students, and students in other health professions. The second edition provides updated examples of how and why the basics of epidemiology are essential to anyone who is required to understand and apply the principles of disease causation and prevention. The book has a particular emphasis on modifiable environmental factors and encourages the application of epidemiology to the prevention of disease and the promotion of health, including environmental and occupational health. It prepares members of the health-related professions to respond to the need for health services to address all aspects of the health of populations, and to ensure that health resources are used to the best possible effect. It shows how good clinical practice is informed by clinical epidemiology; and its lively, concise style is designed to stimulate a continuing interest in the subject. This edition includes comprehensive chapters on the nature and uses of epidemiology; the epidemiological approach to defining and measuring the occurrence of health-related states in populations; the strengths and limitations of epidemiological study designs, causation, the contribution of epidemiology to the prevention of disease, the promotion of health and the development of health policy, and the role of epidemiology in evaluating the effectiveness and efficiency of health care. It enables students to describe the common causes of death, disease and disability in her or his community; outline appropriate study designs to answer specific questions concerning disease causation, nat

Berne and Levy Physiology has long been respected for its scientifically rigorous approach and now includes major updates to bring you all of the latest knowledge in the field. Bruce M. Koeppen and Bruce A. Stanton present a honed and shortened edition that emphasizes the core information needed by students of physiology today and features a full-color design and artwork to enhance readability and enrich your comprehension of every concept. With access to the full contents online at Student Consult, this time-honored book delivers an in-depth understanding of physiology more powerfully and effectively than ever before.

• Describes all of the mechanisms that control and regulate bodily function using a clear and intuitive organ system-based approach.
• Provides a rich understanding of the body's dynamic processes through key experimental observations and examples.
• Includes Student Consult access to the complete and searchable contents of the book online, as well as relevant bonus content from other Student Consult titles, an image gallery, 10 physiology animations, and much more.

• Features updated coverage throughout to expand your understanding of the most current trends in physiology and medicine, including the latest cellular and molecular knowledge.
• Includes shaded boxes that highlight and explain important clinical and molecular information.
• Presents new section editors who ensure that you are getting the freshest, most clinically relevant information available today.
• Summarizes need-to-know information in each chapter with Key Points sections.

This edition covers all aspects of the subject needed by medical students. It is a volume in the Illustrated Colour Text series, with the subject matter divided into double-page spreads; this makes the information very accessible to the reader. Full use is made of flow charts and other graphics; clinical "boxes;" summary points; case histories; and clinical photographs. The whole orientation of the book is to concentrate on how clinical biochemistry relates to the care of the patient and to ensure that the medical student understands how to interpret laboratory.

• Covers clinical biochemistry from the point of view of the clinician using the diagnostic service
• Presents topics in easily accessible two-page spreads
• Includes mini case histories, key point boxes, flowcharts, and summary points
• Well illustrated with four-color drawings and clinical photographs

• New appendix added of annotated web resources for students to take further many of the topics covered in the book.
• To reflect the difficulties people have sometimes in analyzing hyper- and hypo-kalaemia, the existing spread is split into two - one spread on hyperkalaemia and another on hypokalaemia.
• The spread on hypertension will be revised and updated to reflect the fact that biochemistry is used as much or more in guiding treatment as it is in screening for secondary hypertension.
• Spreads on Myocardial Infarction, Cancer and Tumour Markers will all substantially revised and updated.
  

The fourth edition of Clinical Examination provides a clear, practical and above all, superbly illustrated guide to all aspects of history taking and patient examination. Designed to be accessible both to medical students just starting their clinical attachments and to more experienced readers, the clear writing style, the innovative use of clinical photographs and the explanatory illustrations combine to explain and clarify the concepts and skills necessary to take a history and perform an examination. The text is organised by body system, with each chapter structured the same way: firstly, underlying structure and function; secondly, signs, symptoms and abnormalities; thirdly, patient examination.

• The anatomy & physiology coverage 'sets the scene' and refreshes students' memory on the science they studied earlier in their course
• The signs & symptoms sections serve as a mini-textbook of medicine by highlighting most important diseases associated with each body system
• The history-taking and examination sections alert students to general principles and particular considerations relevant to interacting with patients
• Eight different types of boxes classify information on key aspects of the text: differential diagnosis; emergency topics; examination of the elderly; questions to ask; areas for review; risk factors; symptoms and signs; and ‘red flag’ issues
• Nearly 1000 illustrations, including over 500 photographs of physical signs as they present in real life
• Colour diagrams illustrate underlying structure and function as well as demonstrating examination techniques
• Now available on Student Consult with full online access to the text and illustrations

• An expanded author team includes representatives from primary care to reflect the changes in the teaching environment for clinical skills
• A new first chapter focuses more strongly on communication skills and ethics
• New ‘red flag’ highlight important symptoms and signs requiring urgent attention
• Online access to the text and illustrations on Student Consult for the first time
• A revised text design givers the text a fresh feel and aids navigation through the book

So you think you've got a handle on therapeutic management? How drugs work and interact with each other, how the body handles them and how drug treatments are assessed?

This self-assessment volume allows you to learn, revise and test yourself on all aspects of clinical pharmacology and therapeutics. Four different question types are provided to test your knowledge in this important area - multiple choice questions, extended matching questions, 'best of fives' and problem-solving questions. Detailed explanatory answers ensure this book solves your queries as well as providing essential revision for those all-important exams.

Test your knowledge with Clinical Pharmacology and Therapeutics: Questions for Self Assessment and not only develop your exam technique but become a better prescriber.

This book presents a logical system of critical appraisal, to allow readers to evaluate studies and to carry out their own studies more effectively. This system emphasizes the central importance of cause and effect relationships. Its great strength is that it is applicable to a wide range of issues, and both to intervention trials and observational studies.

This system unifies the often different approaches used in epidemiology, health services research, clinical trials, and evidence-based medicine, starting from a logical consideration of cause and effect. The author's approach to the issues of study design, selection of subjects, bias, confounding, and the place of statistical methods has been praised for its clarity and interest. Systematic reviews, meta-analysis, and the applications of this logic to evidence-based medicine, knowledge-based health care, and health practice and policy are discussed. Current and often controversial examples are used, including screening for prostate cancer, publication bias in psychiatry, public health issues in developing countries, and conflicts between observational studies and randomized trials. Statistical issues are explained clearly without complex mathematics, and the most useful methods are summarized in the appendix.

The final chapters give six applications of the critical appraisal of major studies; randomized trials of medical treatment and prevention, a prospective and a retrospective cohort study, a small matched case-control study, and a large case-control study. In these chapters, sections of the original papers are reproduced and the original studies places in context by a summary of current developments.